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I have a Dean Biscuit Bridge Chrome Plated Steel body resonator guitar, 14 fret neck. A made in Korea job. Nice maple neck and Grover Tuners. At the 12th fret it is a full 1/2 step sharp when fretted. Using a slide and pressing hard directly over the fret it seems to be a little better but still not correct. Can this intonation problem be corrected by moving the bridge? If so which direction? I'm also considering trying a Quarterman Cone. Will a new cone help correct the intonation? The bridge appears to be in a slot in the biscuit and perhaps it's not moveable.

First off if you're going to replace the cone go with a National, much better than the Q-mans.

You can usually move the entire cone around a little and if you loosen the screw under the biscuit there is usually some adjustment there too. You can also add some compensation on the saddle itself by turning the biscuit and re-filing the slots at an angle.
If you really want to go all out put in a 1/4" wide saddle and do it up similar to an archtop's.